Назад

Кафедра микробиологии

Направления работы
  • изучение механизмов и роли подвижности и автоагрегации в патогенезе бактериальных инфекций
  • изучение распространения устойчивости к антибиотикам среди возбудителей нозокомиальных инфекций
  • изучение механизмов действия низкотемпературной газовой плазмы как средства терапии инфицированных ран
  • изучение и использование в регенеративной медицине бактериальных агонистов рецепторов факторов роста


    • Основные публикации за последние годы
    1. Domnin P, Arkhipova A, Petrov S,Sysolyatina E, Parfenov V, Karalkin P,Mukhachev A, Gusarov A, Moisenovich M, Khesuani Y, Ermolaeva S. 2020. An in vitro model of nonattached biofilm-like bacterial aggregates based on magnetic levitation. Appl.Environ Microbiol 86:e01074-20. https://doi.org/10.1128/AEM.01074-20. Q1
    2. Domnin, P.A.; Parfenov, V.A.; Kononikhin, A.S.; Petrov, S.V.; Shevlyagina, N.V.; Arkhipova, A.Y.; Koudan, E.V.; Nezhurina, E.K.; Brzhozovskiy, A.G.; Bugrova, A.E.; Moysenovich, A.M.; Levin, A.A.; Karalkin, P.A.; Pereira, F.D.A.S.; Zhukhovitsky, V.G.; Lobakova, E.S.; Mironov, V.A.; Nikolaev, E.N.; Khesuani, Y.D.; Ermolaeva, S.A. Combined Impact of Magnetic Force and Spaceflight Conditions on Escherichia coli Physiology. Int. J. Mol. Sci. 2022, 23, 1837. https://doi.org/10.3390/ijms23031837 Q1
    3. Abdulkadieva, M.M., Sysolyatina, E.V., Vasilieva, E.V. A. I. Gusarov, P. A. Domnin, D. A. Slonova, Y. M. Stanishevskiy, M. M. Vasiliev, O. F. Petrov & S. A. Ermolaeva. Strain specific motility patterns and surface adhesion of virulent and probiotic Escherichia coli. Sci Rep 12, 614 (2022). https://doi.org/10.1038/s41598-021-04592-y Q1
    4. Abdulkadieva MM, Sysolyatina EV, Vasilieva EV, Litvinenko VV, Kalinin EV, Zhukhovitsky VG, Shevlyagina NV, Andreevskaya SG, Stanishevskyi YM, Vasiliev MM, Petrov OF, Ermolaeva SA. Motility provides specific adhesion patterns and improves Listeria monocytogenes invasion into human HEp-2 cells. PLoS One. 2023 Aug 31;18(8):e0290842. http://doi: 10.1371/journal.pone.0290842
    5. Ermolaeva, S.A.; Parfenov, V.A.; Karalkin, P.A.; Khesuani, Y.D.; Domnin, P.A. Experimentally Created Magnetic Force in Microbiological Space and On-Earth Studies: Perspectives and Restrictions. Cells 2023, 12, 338. https://doi.org/10.3390/cells12020338, Q1
    6. Slonov, A.; Abdulkadieva, M.; Kalinin, E.; Bondareva, N.; Kapotina, L.; Andreevskaya, S.; Shevlyagina, N.; Sheremet, A.; Sysolyatina, E.; Zhukhovitsky, V.; Ermolaeva S. et al. The Small Molecule Inhibitor of the Type III Secretion System Fluorothiazinone Affects Flagellum Surface Presentation and Restricts Motility in Gram-Negative Bacteria. Antibiotics 2025, 14, 820. https://doi.org/10.3390/antibiotics14080820
    7. Kalinin EV, Chalenko YM, Sysolyatina EV, Midiber KY, Gusarov AM, Kechko OI, Kulikova AA, Mikhaleva LM, Mukhachev AY, Stanishevskyi YM, Mitkevich VA, Sobyanin KA, Ermolaeva SA. Bacterial hepatocyte growth factor receptor agonist stimulates hepatocyte proliferation and accelerates liver regeneration in a partial hepatectomy rat model. Drug Dev Res. 2021 Feb;82(1):123-132 https://doi.org/10.1002/ddr.21737
    8. Chalenko YM, Sysolyatina EV, Sobyanin KA, Kapkaeva MR, Lavrikova A, Kalinin E, Scheglovitova ON, Ermolaeva SA. Topical treatment with the bacterium-derived c-Met agonist InlB(321)/15 accelerates healing in the abrasion wound mouse model. Arch Dermatol Res. 2018 Dec;310(10):849-856. doi: 10.1007/s00403-018-1870-4
    9. Chalenko Ya; Kalinin E; Marchenkov V; Sysolyatina E; Surin A; Sobyanin K, Ermolaeva S. Phylogenetically Defined Isoforms of Listeria monocytogenes Invasion Factor InlB Differently Activate Intracellular Signaling Pathways and Interact with the Receptor gC1q-R Int. J. Mol. Sci. 2019, Volume 20, Issue 17, 4138 doi: 10.3390/ijms20174138. Q1
    10. Psareva EK, Liskova EA, Razheva IV, Yushina YK, Grudistova MA, Gladkova NA, Potemkin EA, Zhurilov PA, Sokolova EV, Andriyanov PA, Voronina OL, Kolbasov DV, Ermolaeva SA. Diversity of Listeria monocytogenes Strains Isolated from Food Products in the Central European Part of Russia in 2000-2005 and 2019-2020. Foods. 2021 Nov 12;10(11):2790. doi: 10.3390/foods10112790. PMID: 34829070; PMCID: PMC8617672
    11. Andriyanov PA, Zhurilov PA, Liskova EA, Karpova TI, Sokolova EV, Yushina YK, Zaiko EV, Bataeva DS, Voronina OL, Psareva EK, Tartakovsky IS, Kolbasov DV, Ermolaeva SA. Antimicrobial Resistance of Listeria monocytogenes Strains Isolated from Humans, Animals, and Food Products in Russia in 1950-1980, 2000-2005, and 2018-2021. Antibiotics (Basel). 2021 Oct 4;10(10):1206. http://doi: 10.3390/antibiotics10101206. PMID: 34680788; PMCID: PMC8532776
    12. Ermolaeva S, Sysolyatina E, Kolkova N, Bortsov P, Tuhvatulin A, Vasiliev M, Mukhachev A, Petrov A, Tetsuji S, Naroditsky B, Morfill G, Fortov V, Grigoriev A, Zigangirova N, Gintsburg A. Non-thermal argon plasma is bactericidal for the intracellular bacterial pathogen Chlamydia trachomatis. J. Med. Microbiol. 2012. 61:793-799
    13. S.A. Ermolaeva, I.V. Rakovskaya, G.G. Miller, E.V. Sysolyatina, A.Y. Mukhachev, M.M. Vasiliev, R.R. Adgamov, G.A. Levina, O.F. Petrov, G.E. Morfill, A.I. Grigoriev, V.E. Fortov and A.L. Gintsburg. Nonthermal plasma affects viability and morphology of Mycoplasma hominis and Acholeplasma laidlawii. Journal of Applied Microbiology 2014 116(5):1129-1136 DOI: 10.1111/jam.12445
    14. Andriyanov, P.A.; Zhurilov, P.A.; Kashina, D.D.; Tutrina, A.I.; Liskova, E.A.; Razheva, I.V.; Kolbasov, D.V.; Ermolaeva, S.A. Antimicrobial Resistance and Comparative Genomic Analysis of Elizabethkingia anophelis subsp. endophytica Isolated from Raw Milk. Antibiotics 2022, 11, 648